This study is a multicenter retrospective study analyzing the effects of improving weight, blood glucose, and liver function indicators when herbal medicine and a low-carbohydrate diet (LCD, daily carbohydrates ≤50g) are combined without oral medication in patients with early type 2 diabetes.

• The study subjects consisted of 29 patients with HbA1c (glycosylated hemoglobin) of 6.5% or higher who were not taking diabetes treatment medication.
• 72.4% of the subjects achieved clinically significant weight loss of 5% or more, and the average weight loss rate was 9.29%.
• 89.66% of the subjects showed improvement in HbA1c (glycosylated hemoglobin) to 6.5% or less after treatment.

This study is a retrospective multicenter observational study analyzing the effects of Daeat Korean Medicine Clinic's herbal medicine treatment on weight and body composition changes in 40 obese and overweight patients with rheumatoid arthritis (RA).

• The study subjects were RA patients with BMI ≥ 23kg/m², all of whom took herbal medicine containing Ephedra for 90 days, and some used decoctions in parallel.
• As a result, weight significantly decreased by an average of 6.68kg, BMI by 2.60kg/m², body fat mass by 5.54kg, and body fat percentage by 4.20% (p<0.001), and systolic blood pressure also decreased by an average of 11.89mmHg.
• Adverse reactions were mild, such as constipation, insomnia, and palpitations, in a total of 13 patients (32.5%), and most were manageable.

This study is a multicenter retrospective observational study analyzing the effects of parallel treatment with Daeat Korean Medicine Clinic's Dangdaitsdan and a low-carbohydrate diet (LCD) on weight and blood glucose (HbA1c) improvement in 39 patients with obesity and elevated blood glucose (HbA1c ≥ 5.7%).

• Weight decreased by an average of 4.61kg, Body Mass Index (BMI) decreased by an average of 5.24%, 
Body Fat Mass (BFM) decreased by an average of 4.03kg, and significant improvement (p<0.001) was confirmed in all body composition indicators.
• HbA1c levels decreased by an overall average of 0.78%, and in particular, the diabetes patient group (25 patients) showed a 1.23% decrease (p=0.001), indicating a meaningful blood glucose control effect.
• Major interventions used included Dangdaitsdan, a patented herbal medicine of Daeat Korean Medicine Clinic, and auxiliary treatments included pharmacopuncture (LIPOSA, wild ginseng obesity pharmacopuncture, etc.) and LCD dietary guidelines.
• Adverse reactions were mild in 15 patients (38.5%), and safety was confirmed as all were Grade 1. Liver function indicators (AST, ALT, GGT) significantly improved, and there were no changes in renal function and blood pressure indicators.

This study is a retrospective observational study comparing cases of false-positive reactions in amphetamine immunoassay after taking herbal medicine containing Ephedra with cases that turned negative after discontinuation. The study subjects consisted of 6 patients who showed false-positive (FP) results in immunoassay tests among patients who took herbal medicine for diet purposes, and 5 patients who tested negative (Neg) after an average of 5.4 days of discontinuation according to the Korean medicine doctor's instructions before the test.

• False-positive patients were tested while taking an average of 95.17mg of ephedrine-series ingredients for 226 days, and all were confirmed negative in GC-MS re-testing.
• On the other hand, the discontinuation group was negative when tested after taking an average of 88.6mg for 147 days, and there were FP cases even though the Ephedra intake was lower.
• There were a total of 12 adverse reactions in both groups, all of which were Grade 2 (mild), and constipation, insomnia, and palpitations were reported.

This study is a retrospective observational study on a case where trimethylaminuria (TMAU) was suspected due to body odor changes in a patient taking herbal medicine for diet purposes.

• The patient complained of a fishy odor (NRS 8.5, COI level 4) while taking Daitsdan and Dangguijakyaksangagam, and the odor symptoms gradually alleviated after changing the prescription to Injinoryeongsangagam.
• After 4 months, NRS and COI improved to 0, and symptoms did not recur until 2 months after treatment ended.
• Weight decreased by 5.26%, Body Fat Percentage decreased by 8.7%, and Muscle Mass increased, blood pressure indicators were generally within the normal range, and weight loss was achieved safely overall.

This study is a case report analyzing the effects of weight loss and blood glucose (HbA1c) improvement by applying Daeat Korean Medicine Clinic's herbal medicine treatment to 3 patients with type 1 diabetes (Type 1 Diabetes, T1D) who developed obesity due to weight gain during insulin treatment. All patients were prescribed Daitsdan-based herbal medicine containing Ephedra, and some underwent carbohydrate intake restriction and parallel exercise.

• Average weight loss of 10.4kg (5.3~22.8%), all lost more than 5%, which is the clinically significant criterion (MCID)
• HbA1c improvement (Case 1: 7.7→6.7%, Case 2: 7.8→6.5%), significantly decreased below the threshold (7.0%)
• Adverse reactions were all at a mild Grade 1 level, and were only temporary symptoms such as sleep onset disorder, constipation, and indigestion

This study is a retrospective multicenter observational study evaluating the 60-day treatment effects of parallel treatment with Daeat Korean Medicine Clinic's herbal medicine treatment and a low-carbohydrate diet (LCD, 50g carbohydrate limit per day) for 14 patients with inflammatory bowel disease (IBD, ulcerative colitis and Crohn's disease).

• Weight decreased by an average of 5.02kg (6.88%), BMI decreased by 1.84kg/m², Body Fat Mass (BFM) decreased by 4.42kg, and Body Fat Percentage (PBF) decreased by 3.76%. Statistically and clinically significant improvement (p<0.001) was confirmed in all.
• Adverse reactions occurred in 7 patients (50%) at a mild or moderate level (Grade 1~2) such as nausea, indigestion, headache, etc., and there were no serious side effects.
• In terms of IBD symptom progress, normalization of bowel movement frequency, improvement of stool condition, and alleviation of bloody stool, diarrhea, and constipation appeared in many patients, and 1 patient even stopped drug treatment due to symptom improvement.

This study is a retrospective multicenter study evaluating the liver function improvement effect and safety of herbal medicine-based obesity treatment performed at Daeat Korean Medicine Clinic for 84 obese patients with elevated liver enzyme levels (AST, ALT, GGT).
 The treatment period was an average of 158.8 days or more, and all patients took solid-form herbal medicine containing Ephedra, and 81 patients also took decoctions containing Injinho in parallel.

• AST: 44.73 → 25.70 U/L (average -19.02) ALT: 66.24 → 32.27 U/L (average -33.96) GGT: 78.04 → 51.56 U/L (average -26.48) Significantly improved to the normal range in all items (p<0.001)
• Average weight loss of 5.89kg
• BMI: average 2.16 kg/m² decrease
 Both weight and BMI achieved MCID criterion-exceeding weight loss

This study is a multicenter retrospective observational study analyzing the clinical effectiveness of LIPOSA by comparing cases of local obesity patients who received parallel herbal medicine treatment and LIPOSA pharmacopuncture with those who received herbal medicine treatment alone. Data from 117 patients at 6 Korean medicine medical institutions from January 2023 to April 2024 were analyzed, of which 62 were in the LIPOSA group (herbal medicine + pharmacopuncture), and 55 were in the control group (herbal medicine alone).

• The LIPOSA group showed weight -6.45%, BMI -6.17% decrease, especially Body Fat Mass -4.20kg, Body Fat Percentage -3.20% decrease, showing significant improvement compared to the control group (p<0.01).
• Skeletal muscle mass decrease was relatively smaller in the LIPOSA group.(-0.26kg vs -0.45kg)
• In terms of IBD symptom progress, normalization of bowel movement frequency, improvement of stool condition, and alleviation of bloody stool, diarrhea, and constipation appeared in many patients, and 1 patient even stopped drug treatment due to symptom improvement.

This study is a literature review research that explored the theoretical background and actual diagnostic application possibility of Bian Que's pulse method based on ancient medical literature, focusing on the pulse diagnosis method (pulse method) of Bian Que (扁鵲) appearing in the "Yellow Emperor's Inner Canon" and later medical books.

• Extracted technical descriptions related to Bian Que's pulse method from classic literature such as "Yellow Emperor's Inner Canon", "Classic of Difficult Issues", and "Treatise on Cold Damage Diseases"
• Emphasized the characteristics as a 'comprehensive pulse diagnosis method' that comprehensively diagnoses the location, speed, depth, strength, and dynamics of the pulse
• Interpretation of a dynamic diagnostic system that looks at the entire progress and flow of the disease, not just looking at the six pulses (Cun, Guan, Chi) or surface/interior, cold/heat only
• Presented the inference method of pulse interpretation and clinical application possibility through expressions such as "五藏有病 而知其所生"

This study is a literature review research that organized the diagnostic system of the Bian Que school (扁鵲學派), composed of the legendary ancient Chinese physician Bian Que (扁鵲) and his ideological successors, and analyzed its medical principles and connection with modern Korean medicine diagnostic methods.

• Analysis of Bian Que's diagnostic methods appearing in ancient literature such as "Records of the Grand Historian" (史記) "Biography of Bian Que and Cang Gong" and "Yellow Emperor's Inner Canon", "Classic of Difficult Issues"
• Among the four diagnostic methods (四診) of "Looking, Listening, Asking, and Feeling", especially emphasized Asking (問診) and Feeling (切診, pulse diagnosis)
• Bian Que judged the location, nature, and progress of the disease through direct communion and precise observation with the patient, which was aimed at comprehensively judging the patient's constitution and the imbalance state of organ functions, not just a simple disease name diagnosis
• Later Bian Que school physicians inherited this and established a diagnostic system that considers everything from pulse condition + symptoms + medical history + environment integrally when diagnosing

This study is a literature-based data analysis research that presented a methodology to quantitatively infer and classify the efficacy of formulas (prescriptions) based on the composition information of herbal medicines (medicinal materials) used in traditional herbal medicine prescriptions. The research subjects were various prescriptions recorded in "Bangyakhapyeon", and an inference model was developed based on herbal composition ratios and efficacy information.

• Herbal classification-based method: Deriving main efficacy by utilizing the classification of herbs within the prescription (e.g., blood tonifying, qi-regulating, etc.) and weight ratios
• Herbal efficacy-based method: Calculating formula efficacy by multiplying the efficacy information and weight ratio of each herb
• Formula study textbook-based inference: Deriving the efficacy intensity of individual herbs by reflecting formula efficacy frequency and composition ratios, and quantitatively inferring representative efficacy
• Representative efficacy of prescriptions can be inferred from herbal composition alone
• The model considering efficacy intensity allows for the clearest efficacy inference
• Multidimensional efficacy analysis is more efficient than simple classification-based analysis

This study is a large-scale retrospective study analyzing the improvement effects on weight, blood pressure, and metabolic indicators when herbal medicine including Daitsdan and lifestyle habit correction through the Daeat app were combined in obese patients with a BMI of 30 or higher.

• The study subjects consisted of 3,161 obese patients with a BMI of 30 or higher.
• 67.9% of the subjects achieved clinically significant weight loss of 5% or more, and the average weight loss rate was 8.71%.
• In the 'Optimal Group (24 patients)', an average of 23.0kg (28.4%) weight loss was achieved, and BMI recovered to the normal range (under 23), and blood pressure indicators also significantly improved.

This study is a retrospective chart review analyzing the effectiveness, satisfaction, and safety of Korean medicine treatment based on patient feedback surveys from the Korean medicine medical station operated at the National Shooting Competition site from May to July 2025.

• The study subjects consisted of 111 patients (59.5% male, 40.5% female) who received treatment at the National Shooting Competition Korean medicine medical station and participated in the feedback survey.
• The Korean medicine medical station provided various Korean medicine treatments such as acupuncture, electroacupuncture, infrared irradiation, cupping, herbal patches, and herbal medicine (Banhasasimtang, Bieumdan).
• Pain NRS score after treatment decreased by an average of 2.3 points, showing a statistically significant effect, which is a result exceeding the Minimal Clinically Important Difference (MCID 2.0 points).
• Patient satisfaction was very high, with overall satisfaction averaging 5.0 points, and intention to receive re-treatment and recommend to others averaging 4.8 points each, with most respondents choosing 'very satisfied'.

This study is a retrospective study that selected 6 patients whose eGFR increased after treatment among patients who visited Daeat Korean Medicine Clinic Incheon Bupyeong branch for obesity treatment from December 2023 to July 2025.

• The study subjects consisted of 6 patients (including 3 with mild renal function impairment) who took Banchongsan and had both pre- and post-treatment renal function tests and body composition measurements, and whose eGFR increased after treatment.
• All patients were administered Banchongsan decoction and restricted carbohydrate intake to 50~60g per day.
• 5 out of 6 patients showed MCID (5% or more) weight loss, and weight and body fat mass reduction and eGFR improvement were observed simultaneously.

This study is a case report targeting an adolescent patient born in 2009, aged 15, who visited Daeat Korean Medicine Clinic Seoul branch from October 2024 and took herbal medicine for weight loss.

• The patient received growth treatment at a university hospital in Seoul for a long period due to growth delay, and clinical growth hormone treatment was terminated in September 2024.
• The patient is a female adolescent born in 2009 who had continuous weight gain of about 8kg from around January 2024, and treatment was conducted at our clinic from October 2024 to July 2025.
• During the treatment period, height increased by 1.6cm, and the reproductive hormone indicator Estradiol rose from 12.4 pg/mL to 57.5 pg/mL, and menstrual cycle recovered for 4 consecutive months, FSH and LH also recovered to ranges appropriate for the age group.

This study is a research that comprehensively organized randomized controlled trials (RCTs) of herbal medicine related to postmenopausal obesity published domestically and internationally up to September 2025.

• The herbal medicine treatment group showed significant improvement in major obesity indicators such as weight, BMI, waist circumference, and waist-hip ratio compared to the control group.
• In two studies, hormone imbalance alleviation effects such as increased estradiol and decreased follicle-stimulating hormone and luteinizing hormone levels were observed.
• Depression assessment scores and menopausal symptom scores significantly improved in the treatment group.

This study is a survey-based observational study targeting 33 students enrolled in the 'Surgery and Practice 2' course at Gachon University College of Korean Medicine who took the final exam conducted via CBT on December 18, 2024.

• 30 of them responded to the survey, and the gender of the respondents was 50% female, and the age was 26.4±2.0 (24-31) years old.
• The ratio of responding that they had experienced CBT before was 43.3% (13 students), and regarding familiarity with computer use, 'very familiar' and 'somewhat familiar' each accounted for 43.3% (13 students).
• As a result of the study, overall satisfaction was 4.23/5 points, and intention to use CBT continuously in the future was 4.10/5 points, which were high, and utilization of high-definition visual materials and ease of time management were confirmed as major advantages compared to PBT.

This study is a retrospective analysis of eating attitude changes in 153 adults who combined Korean medicine treatment and nutritionist intensive coaching (LCD-based) at Daeat Korean Medicine Clinic multicenters (Seoul, Busan, etc.).

• After nutritionist intensive coaching, bulimia/food preoccupation scores significantly decreased, showing a tendency for obsession with food and binge eating behavior to be alleviated.
• On the other hand, oral control scores increased due to increased awareness of carbohydrate avoidance and diet management, which increased the existing KEAT-26 total score.
• However, in an analysis that adjusted 5 items reflecting the characteristics of low-carbohydrate diet education, the proportion of high-risk groups for eating attitudes significantly decreased from 53.6% to 26.1%.

This study is a retrospective chart review targeting patients who visited as first-time patients and participated in the Daeat Detox Diet Program at 4 branches, including Daeat Korean Medicine Clinic Seoul, Incheon Bupyeong, Gyeonggi Suwon, and Gyeonggi Ilsan, from September to October 2024.

• Among 915 first-visit patients, 25 patients who visited immediately after the program were included in the study as a sample.
• About 72% of the study subjects corresponded to obesity of stage 1 or higher, and the average number of past diet attempts was 2.93.
• Complex herbal medicine was combined, including Daitsbalance (LCD), Bieumdan (containing rhubarb), and Detoxdan (containing Ephedra), for 3 days.
• After implementing the Detox Diet Program, BMI, weight, skeletal muscle mass, and body fat mass significantly decreased, and there was no significant change in skeletal muscle percentage. This suggests that it is effective for weight and body fat reduction and stability in terms of muscle ratio preservation was confirmed.

This study is a scoping review analyzing diabetes-related Korean medicine research published in domestic academic journals from 2015 to 2024.

• Systematically analyzed the research types, intervention methods, and trends of clinical evaluation indicators targeting a total of 74 papers.
• Experimental research (23 papers, 31.1%) and case reports (28 papers, 37.8%) accounted for the majority, and retrospective clinical research (11 papers, 14.9%) utilizing actual patient data also increased.

This study is a multicenter retrospective study targeting adult patients with a confirmed history of angina pectoris among first-visit patients who started a weight loss program at Daeat Korean Medicine Clinic from January 2021 to July 2025.

• 51 adult patients with a history of angina pectoris diagnosis from 6 branches were included in the final analysis.
• Among the study subjects, 46 patients (90.2%) were taking related medications, and 13 patients (25.5%) had a history of past stent procedures.
• Average weight decreased by about 7kg, and about 80% of all patients lost 5% or more of their weight.
• Systolic blood pressure decreased by an average of 6mmHg, and heart rate decreased by an average of 7 or more beats, maintaining a range of less than 80 beats on average.
• Although Ephedra-containing herbal medicine, for which cardiovascular safety controversy was raised due to the possibility of sympathetic nervous system stimulation, was used, no adverse reactions were reported.

This study is a single-center retrospective observational study evaluating muscle preservation effects by analyzing BIA and HGS changes targeting adult male patients who underwent Korean medicine obesity treatment at Daeat Korean Medicine Clinic Seoul branch.

• The study subjects were male patients who took solid-form herbal medicine for at least 90 days, totaling 46 patients.
• Average age was 40, average weight at first visit was 94.2kg, average BMI was 31.2kg/㎡, average height was 173.8cm, and average treatment period was 132.4 days.
• Weight decreased by 9.6kg and body fat by 7.1kg, which were statistically significant.
• SMM decreased, but SM% increased by 2.8%, and RGS also significantly improved, suggesting the possibility of body fat-centered weight loss and muscle function preservation.

This study is a retrospective observational study targeting elderly people residing in the Gwangmyeong Municipal Nursing Center who participated in a Korean medicine weight management program for 90 days from September to December 2025.

• All study subjects have underlying diseases such as hypertension, dementia, stroke sequelae, etc.
• There were a total of 11 study subjects, and blood glucose treatment herbal medicine Dangchaitsdan prescription and low-carbohydrate diet education were conducted for the obesity group (6 patients).
• Gyeongokgo prescription and low-carbohydrate diet education for systemic weakness improvement were conducted for the underweight group (5 patients).
• Body fat mass and BMI decreased in all subjects, and some indicators such as muscle strength, K-FRAIL, mYFAS, etc., showed improvement in the obesity group, while no clear changes in body composition, nutritional status, and functional indicators were confirmed in the underweight group.

This study is a multicenter retrospective chart review analyzing the medical records of patients who attached a Continuous Glucose Monitor (CGM) among patients receiving Korean medicine obesity treatment.

• The study subjects were 31 patients who wore CGM for 14-15 days.
• Standardized obesity herbal medicine (solid-form and decoction) prescription and low-carbohydrate diet of Daeat Korean Medicine Clinic were combined for all subjects.
• 2 weeks after starting treatment, Time in Range (TIR) increased by an average of 8.46%p.
• 1 month after starting treatment, average weight decreased by 3.6kg, and blood pressure and HbA1c also improved together, confirming indicator changes even in the short term.

This study is a multicenter retrospective observational study analyzing the distribution of decoction prescriptions and prescription group transition patterns occurring in actual clinical environments.

• A total of 23,950 patients at 8 branches were included in the analysis.
• The average age of the study subjects was 43.6±12.0 years (5-96 years), IQR was 44 years (34-53 years), and age distribution was in the order of 40s (28.0%), 50s (25.4%), and 30s (24.6%).
• 16,461 patients (68.7%) maintained a single prescription group during the treatment period, 4,961 patients (20.7%) experienced 2 prescription groups, and 2,528 patients (10.6%) experienced 3 or more prescription groups, so prescription group changes were observed in 31.3% of all patients.

This study is a research analyzing the effectiveness and safety of Sasang constitution-based obesity treatment targeting Taeeumin overweight/obese patients.

• Among overweight/obese patients who received Taeeumin prescriptions, 590 who continued treatment for 12 weeks or more were included in the analysis.
• The study subjects were centered on herbal medicine administration, and pharmacopuncture and device treatment were combined according to the condition, and dietary guidelines for lifestyle habit correction were provided equally to all subjects.
• Average weight -7.99±7.15 ㎏, BMI -2.46±2.71 ㎏/㎡, body fat mass -6.72±5.95㎏, body fat percentage -3.77±4.20% appeared, and all significantly decreased compared to before treatment.

This study is a research that systematically examined obesity treatment-related research listed in international academic databases over the past 5 years by utilizing the Scoping Review methodology.

• According to the selection and exclusion criteria, a total of 26 literature were selected as analysis subjects.
• 88.5% of the analysis subjects adopted RCT design, so the methodological level of clinical evidence was enhanced, and as treatment types, embedding therapy 12 papers, acupuncture-based treatment 7 papers, herbal medicine treatment 5 papers were in high frequency order.
• Evaluation indicators included metabolic indicators such as insulin resistance, lipid metabolism, leptin/adiponectin along with physical measurement indicators such as waist circumference, body fat percentage, and expanded to fMRI and gut microbiota analysis.
• In terms of safety, 15 out of 26 papers (57.7%) explicitly reported adverse reactions and safety, and serious adverse reactions were rare.